HyalOne®

HyalOne^® is a sterile, non-pyrogenic, viscoelastic solution manufactured with hyaluronic acid sodium salt.

In traumatic and degenerative joint disorders, an insufficient amount of hyaluronic acid and a loss of viscosity occur in synovial fluid, resulting in an impairment of joint function and in a painful symptomatology¹. Extensive data in the literature indicate that intra-articular administration of hyaluronic acid is capable to restore the visco-elastic properties of the synovial fluid, with alleviation of pain and improvement of joint mobility².

Features

Natural non-crosslinked hyaluronic acid
Well-defined high molecular weight of 1,500-2,000 kDA
High hyaluronic acid dose of 60 mg/ 4 mL
“One-shot” administration
Long duration of effect up to 12 months³
Optimal tolerability
Manufacturer with over 60 years of expertise in hyaluronic acid research and development

Composition: Hyaluronic acid sodium salt 1.5%

Indication: HyalOne^® is a temporary synovial fluid replacement for patients affected by degenerative or mechanical arthropathy of the hip and knee, that causes an alteration of the functional performances of the synovial liquid, without active synovitis.

Dosage: Product administration shall be performed exclusively by qualified doctors.

Pack Size: Product administration shall be performed exclusively by qualified doctors.

Precaution: For details, please refer to package insert.

Storage

Store at a temperature not exceeding 25 °C.
Keep out of reach of children.

Disclaimer & Reference

The content on this site is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician with any questions you may have regarding a medical condition.

Reference

Sprott H, Fleck C. Hyaluronic Acid in Rheumatology. Pharmaceutics. 2023;15(9):2247. doi:10.3390/pharmaceutics15092247
Altman R, Manjoo A, Fierlinger A, Niazi F, Nicholls M. The mechanism of action for hyaluronic acid treatment in the osteoarthritic knee: a systematic review. BMC Musculoskelet Disord. 2015;16:321. doi:10.1186/s12891-015-0775-z
Migliore A, Massafra U, Bizzi E, et al. Intra-articular injection of hyaluronic acid (MW 1,500-2,000 kDa; HyalOne) in symptomatic osteoarthritis of the hip: a prospective cohort study. Arch Orthop Trauma Surg. 2011;131(12):1677-1685. doi:10.1007/s00402-011-1353-y

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